Not built-in. There are two possible solutions, both of which involve using extensions.
The first solution is to create an inline macro that performs calculations. Something like:
calc:[1 + 2]
However, if you wanted to be able to reference cells, you'd need to introduce some sort of reference shorthand that extracted data from the AST, so depending on what you're after, it could get rather involved.
calc:[:A1 + :A2]
I hope that helps.
Cheers,
-Dan